Scientists working at the US State University of Oregon, announced that they are working on a new cancer treatment approach based on magnetic hyperthermia. In the developed method, magnetic nano particles with a special form are used. These particles can be applied by vessels without reaching directly tumor. Especially in deep -located cancer types, such as ovarian tumors, attracts attention.
The design of Nano particles stands out as a decisive factor in treatment success. The new structure developed by researchers has a form of a stuck cube between the two pyramids. Thanks to this original geometry, the capacity of the particles to produce heat has increased significantly. This makes it possible to reach the targeted temperatures with a lower dose of material.
Particles in its new shape are quickly heating in target texture
These magnetic nano particles have an iron oxide -based structure and are strengthened with a cobalt contribution. When exposed to alternative magnetic fields, they provide temperature increase up to 3.73 ° C per second. This ratio points to about twice the productivity of previous generation similar structures. According to researchers, this performance can offer effective treatment with shorter -term applications.
The method used in the study was created with a production process reported for the first time in the literature. This two -stage synthesis, called “core and growth ((Seed and Growth), allows the production of particles in the desired form. All of the structures obtained are suitable and consistent with the targeted shape. This is considered as an element that increases the reliability of experimental results.
In addition, targeting peptide structures are used to direct Nano particles to the cancerous tissue. In this way, the particles given by vessels are transported directly to the tumor area. Thanks to its high heat efficiency, there is no need to send a high dose of particles to the tumor. This offers an important advantage that reduces the risk of toxic effects in the body.
According to the study, the particles after the systemic application can increase the tumor tissue above 50 ° C with a single 30 -minute magnetic field session. This temperature is well above the 44 ° C limit required to start cell death. This increases the success of treatment while shortening the application time. At the same time, a method that supports patient comfort is revealed.
However, this study is still limited to animal models. Results of the research Advanced Functional Materials published in the magazine. Before moving on human clinical experiments, long -term security and activity assessments need to be completed. Nevertheless, a non -invasive solution proposal for unreachable tumors has been presented.
In addition, these newly developed magnetic nano particles are not limited to ovarian cancer. Researchers, thanks to systemic transportation possibilities, the lungs, pancreas, such as deep tissues in the types of cancer in the species of use, he states that the potential. This means the expansion of the treatment area. It can create a new option, especially for cases that are especially diagnosed but not suitable for surgery.
In any case, numerous verifier work is needed to be widely available for this method. Considering the increasing role of Nano technology in the treatment of cancer, this study is considered an important step. If the transition to clinical practices in the coming years, a significant change may be experienced in existing treatment approaches. The door of an alternative solution for unreachable tumors is opened.
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